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November 18, 2016
American journal of Alzheimer’s disease & other dementias
American journal of Alzheimer’s disease & other
Table of Contents
Top of Form
Simple Neuropsychological Tests May Identify
Participants in Whom Aspirin Use Is Associated With Lower Dementia Incidence:
The Canadian Study of Health and Aging
Background: We hypothesized that neuropsychological tests
could help in identifying preclinical stages of vascular cognitive impairment,
when aspirin use might be associated with lower dementia incidence.
Conclusions: Two simple neuropsychological tests might help in
identifying preclinical stages of vascular cognitive impairment, and salicylates use was associated with
lower dementia incidence.
Shedding a Light on Phototherapy Studies with
People having Dementia: A Critical Review of the Methodology from a Light
Light therapy is applied to older people
with dementia as a treatment to reset the biological clock, to improve the
cognitive functioning, and to reduce behavioral symptoms. … This study reviewed
light therapy studies concerning the effects on people with dementia as a way
to check the methodological quality of the description of light from a light
engineering perspective. Twelve studies meeting the inclusion criteria were
chosen for further analysis. .. The studies describe the lighting
insufficiently and not in the correct metrics. The robustness of light therapy
studies can be improved by involving a light engineer or specialist.
The Effect of Undiagnosed Diabetes on the
Association Between Self-Reported Diabetes and Cognitive Impairment Among Older
To study the effect of undiagnosed diabetes on the relationship between
self-reported diabetes and cognitive impairment.
Discussion: The association between self-reported diabetes and
severe cognitive impairment is underestimated when undiagnosed diabetics are
not differentiated from self-reported diabetics and nondiabetics.
Pilot Testing of the EIT-4-BPSD Intervention
Behavioral and psychological symptoms of dementia
are common in nursing home residents, and the Centers for Medicare and Medicaid
Services now require that nonpharmacological
interventions be used as a first-line treatment. Few staff know how to
implement these interventions. The purpose of this study was to pilot test
an implementation strategy, Evidence Integration Triangle for Behavioral and
Psychological Symptoms of Dementia (EIT-4-BPSD), which was developed to help
staff integrate behavioral interventions into routine care. …A research nurse facilitator worked with
facility champions and a stakeholder team to implement the 4 steps of
EIT-4-BPSD. There was evidence of
reach to all staff; effectiveness with improvement in residents’ quality of
life and a decrease in agitation; adoption based on the environment, policy,
and care plan changes; and implementation and plans for maintenance beyond the
6-month intervention period.
Effects of Acetylcholinesterase Inhibitors on
Balance and Gait Functions and Orthostatic Hypotension in Elderly Patients With
Objective: The present study was designed to evaluate the
effect of acetylcholinesterase inhibitor (AchEI) therapy on balance, gait, and
orthostatic hypotension (OH) in elderly patients with Alzheimer’s disease (AD).
Conclusion: Curative effects of AchEIs, which are used in the
treatment of AD, on cognitive performance are reflected also in balance
functions. Moreover, it was observed that these drugs do not increase the
prevalence of OH.
Clinical Epidemiology, Evaluation, and Management
of Dementia in Parkinson Disease
The prevalence of neurodegenerative diseases such
as Parkinson disease (PD) will increase substantially, due to the aging of the
population and improved treatments leading to better disease-related outcomes.
Dementia is the most common nonmotor symptom in PD, and most patients with PD
will have cognitive dysfunction and cognitive decline in the course of their
disease. The development of cognitive dysfunction in PD greatly limits the
ability to participate in activities of daily living and can be a tipping point
for nursing home placement or major caregiver stress. Understanding the
different causes of dementia and how to reduce the incidence and impact of
secondary cognitive dysfunction in PD are necessary skills for primary care
physicians and neurologists. In this review, we discuss the clinical
epidemiology of dementia in PD with an emphasis on preventable cognitive
dysfunction, present tools for outpatient evaluation of cognitive dysfunction,
and describe current pharmacological treatments for dementia in PD.